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P.T.REC/012/004609

Pivotal influence of obesity on body composition and ovarian doppler in different polycystic ovarian syndrome phenotypes
Source : Importé depuis le centre

Référence clinicaltrials.gov: NCT06164132
Polycystic Ovary Syndrome
Obesity
Body composition
Ovarian Doppler
Source : Importé depuis le centre
Recrutement fermé
Dernière modification : 2024/02/13
Type de recherche

Observationnel


Population cible

Condition médicale (spécialité visée)

Donnée non disponible

Profil des participants

Sexe(s) des participants

FEMALE

Source : Importé depuis le centre

Critères de sélection

Critères d'inclusion

Inclusion Criteria:

* Age ranged from 18 to 40 years old.
* Individuals with Polycystic Ovary Syndrome (PCOS) should exhibit at least two of the three features outlined in the Rotterdam criteria for diagnosis, encompassing oligo- or anovulation, clinical and/or biochemical indications of hyperandrogenism, and the presence of polycystic ovaries as identified through ultrasonography.

Exclusion Criteria:

* Congenital adrenal hyperplasia
* Thyroid dysfunction
* Hyperprolactinemia
* Androgen-secreting tumors
* Cushing syndrome
* Undergoing any medical therapy for the treatment of PCOS or for weight loss.

Source : Importé depuis le centre

Thérapie ou Intervention proposée

Cohortes
Nom Condition médicale Traitement État du recrutement
Normal Weight group Their BMI ranged from 18.5 to 24.9 kg/m2. Donnée non disponible
  • Inconnu
  • Overweight group Their BMI ranged from 25 to 29.9 kg/m2. Donnée non disponible
  • Inconnu
  • Obese group Their BMI was ≥ 30 kg/m2. Donnée non disponible
  • Inconnu
  • Normal Weight group
    État du recrutement
    unknown
    Overweight group
    État du recrutement
    unknown
    Obese group
    État du recrutement
    unknown
    Données à jour depuis : 13 février 2024

    Description de l'étude

    Résumé de l'étude

    The study aimed to explore the impact of obesity on both body composition and ovarian Doppler parameters across various phenotypes of females diagnosed with polycystic ovarian syndrome (PCOS). Additionally, the investigation seeked to establish correlations between these parameters and their prevalence concerning the clinical criteria of PCOS.

    Source : Importé depuis le centre

    Polycystic ovarian syndrome (PCOS) is a complex and multifactorial condition characterized by endocrinological, reproductive, metabolic, and biochemical abnormalities, affecting 12% to 21% of reproductive-aged females. It has emerged as a significant global public health concern. However, variations in diagnostic criteria and patient selection have led to considerable discrepancies in the absolute prevalence of PCOS and its temporal trends. Previous studies have examined ovarian volume and blood flow indices in both obese and non-obese females with PCOS, albeit employing different criteria for obesity classification. Notably, none have compared these parameters across normal weight, overweight, and obese PCOS females. Therefore, the current study aims to explore the impact of obesity on body composition and ovarian Doppler parameters within distinct PCOS phenotypes. An additional objective is to assess correlations between anthropometric, body composition, and ovarian Doppler parameters and the prevalence of PCOS symptoms.

    Source : Importé depuis le centre

    Sites

    Centres participants

      1 centres
    • CAIRO UNIVERSITY

      Giza

      EGYPT

      Recrutement local
      État du recrutement: FERMÉ

    Dernière modification : 13 février 2024
    Données à jour depuis : 2 juil.
    Origine des données : clinicaltrials.gov
    Référence clinicaltrials.gov: NCT06164132