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BCCR - H15-01726

Pilot study in vivo confocal microscopy probe for cervical precancer
Source : Importé depuis le centre

Référence clinicaltrials.gov: NCT02574442
cervical intraepithelial neoplasia grade 1
cervical intraepithelial neoplasia grade 2
cervical intraepithelial neoplasia grade 3
adenocarcinoma in situ
Source : Importé depuis le centre
Precancerous Condition
Cervical Cancer
Recrutement en pause
Dernière modification : 2019/07/01

Population cible

Condition médicale (spécialité visée)

Choix aire thérapeutique

Precancerous Condition

Cervical Cancer

Source : Importé depuis le centre

Profil des participants

Donnée non disponible

Critères de sélection

Critères d'inclusion

Inclusion Criteria:

* indicate understanding of the study
* provide informed consent to participate
* 18 years old or older
* not pregnant and have negative urine pregnancy test
* be schedule for colposcopy \& biopsy at the Vancouver General Hospital Women's Clinic

Exclusion Criteria:

* they are breast-feeding
* they had an operation to remove their cervix

Source : Importé depuis le centre

Thérapie ou Intervention proposée

Cohortes
Nom Condition médicale Traitement État du recrutement
Initial Colposcopy Visit Donnée non disponible Women with a scheduled colposcopy and biopsy appointment at the Women's Clinic at Vancouver General Hospital
  • Inconnu
  • Initial Colposcopy Visit
    État du recrutement
    unknown
    Données à jour depuis : 1 juillet 2019

    Description de l'étude

    Résumé de l'étude

    The goal of this proposal is to determine whether a hand-held confocal microscopy probe may perform better than standard methods in detecting cancer or pre-cancerous abnormalities of the cervix. The confocal probe will provide invivo histopathology-like images of cell morphology and three-dimensional tissue architecture non-invasively in real time.

    Source : Importé depuis le centre

    All subjects will undergo standard management (colposcopy) for their cervical lesion as scheduled. For cervical sites suspicious of dysplasia, acriflavine hydrochloride 0.05% solution will be applied topically, then rinsed with saline prior to in vivo confocal imaging with the hand-held probe. Following that, a biopsy of the suspicious site will be performed irrespective of the confocal microscopy finding. A biopsy of the normal site will be taken for research purposes. The confocal probe imaging will not alter where and how the biopsies will be taken (no change to size of biopsy or location on cervix).

    The procedure will add approximately 15 minutes to the duration of the standard outpatient procedure. During each examination, the anatomical location of all tissue areas in question will be recorded using the clock-position nomenclature system. Some normal areas will be also localized and recorded as control. Digital images will be recorded in the computer.

    Source : Importé depuis le centre

    Sites

    Centres participants

      1 centres
    • VANCOUVER GENERAL HOSPITAL

      Vancouver

      BRITISH COLUMBIA, CANADA

      Recrutement local
      État du recrutement: EN PAUSE

    Dernière modification : 1 juillet 2019
    Données à jour depuis : 1 jan.
    Origine des données : clinicaltrials.gov
    Référence clinicaltrials.gov: NCT02574442